Clima: Céu Limpo Relvado: Céu Limpo
| Uruguai - Liga de Reservas | 2018/05/08 18:00 | Penarol - Reservas v Defensor Sporting - Reservas | D | 1-1 |
| Uruguai - Liga de Reservas | 2017/10/24 18:00 | Penarol - Reservas v Defensor Sporting - Reservas | W | 2-3 |
| Uruguai - Liga de Reservas | 2018/10/24 13:00 | Club Atlético River Plate - Reservas v Defensor Sporting - Reservas | D | 3-3 |
| Uruguai - Liga de Reservas | 2018/10/16 13:00 | Liverpool Montevideo - Reservas v Defensor Sporting - Reservas | L | 1-0 |
| Uruguai - Liga de Reservas | 2018/10/10 18:30 | Torque - Reservas v Defensor Sporting - Reservas | D | 1-1 |
| Uruguai - Liga de Reservas | 2018/10/07 16:30 | Defensor Sporting - Reservas v Montevideo Wanderers - Reservas | W | 3-1 |
| Uruguai - Liga de Reservas | 2018/09/19 18:30 | Defensor Sporting - Reservas v Racing Club de Montevideo - Reservas | D | 1-1 |
| Uruguai - Liga de Reservas | 2018/09/11 13:00 | CA Cerro - Reservas v Defensor Sporting - Reservas | L | 4-2 |
| Uruguai - Liga de Reservas | 2018/09/04 13:00 | Progreso - Reservas v Defensor Sporting - Reservas | W | 0-4 |
| Uruguai - Liga de Reservas | 2018/08/28 13:30 | Defensor Sporting - Reservas v Club Nacional - Reservas | W | 2-0 |
| Uruguai - Liga de Reservas | 2018/10/30 13:00 | Penarol - Reservas v Progreso - Reservas | W | 4-2 |
| Uruguai - Liga de Reservas | 2018/10/20 15:15 | Club Nacional - Reservas v Penarol - Reservas | L | 4-0 |
| Uruguai - Liga de Reservas | 2018/10/16 13:00 | Penarol - Reservas v Atlético Fénix - Reservas | W | 4-0 |
| Uruguai - Liga de Reservas | 2018/09/30 17:37 | Rampla Juniors - Reservas v Penarol - Reservas | D | 0-0 |
| Uruguai - Liga de Reservas | 2018/09/26 13:00 | Penarol - Reservas v Torque - Reservas | W | 2-1 |
| Uruguai - Liga de Reservas | 2018/09/19 18:00 | Danubio - Reservas v Penarol - Reservas | D | 1-1 |
| Uruguai - Liga de Reservas | 2018/09/12 14:00 | Penarol - Reservas v Atenas - Reservas | W | 3-0 |
| Uruguai - Liga de Reservas | 2018/09/05 13:00 | Penarol - Reservas v CA Cerro - Reservas | W | 3-1 |