Head to Head
| Copa Chile | 2016/09/15 23:00 | Cobreloa v La Serena | L | 3-0 |
| Chile - Primera B | 2016/04/09 21:00 | Cobreloa v La Serena | W | 2-3 |
| Chile - Primera B | 2015/11/07 20:00 | La Serena v Cobreloa | D | 0-0 |
Home History
| Chile - Primera B | 2016/09/24 21:00 | La Serena v Curico Unido | L | 0-2 |
| Copa Chile | 2016/09/15 23:00 | Cobreloa v La Serena | L | 3-0 |
| Chile - Primera B | 2016/08/27 22:00 | Puerto Montt v La Serena | D | 1-1 |
| Chile - Primera B | 2016/08/20 21:00 | La Serena v Magallanes | D | 0-0 |
| Chile - Primera B | 2016/08/14 18:30 | Iberia v La Serena | L | 3-2 |
| Chile - Primera B | 2016/08/07 19:30 | La Serena v Coquimbo Unido | D | 1-1 |
| Chile - Primera B | 2016/07/31 19:30 | Santiago Morning v La Serena | L | 3-0 |
| Copa Chile | 2016/07/17 19:00 | Santiago Wanderers v La Serena | L | 2-1 |
Away History
| Chile - Primera B | 2016/09/25 19:00 | Cobreloa v Rangers de Talca | W | 4-0 |
| Copa Chile | 2016/09/15 23:00 | Cobreloa v La Serena | W | 3-0 |
| Chile - Primera B | 2016/09/10 23:00 | Ñublense v Cobreloa | L | 2-0 |
| Chile - Primera B | 2016/08/28 19:00 | Cobreloa v San Marcos De Arica | D | 0-0 |
| Chile - Primera B | 2016/08/21 18:30 | Union San Felipe v Cobreloa | L | 3-2 |
| Chile - Primera B | 2016/08/07 20:00 | Cobreloa v Iberia | D | 2-2 |
| Chile - Primera B | 2016/07/30 20:00 | Coquimbo Unido v Cobreloa | L | 1-0 |
| Copa Chile | 2016/07/17 20:00 | Antofagasta v Cobreloa | D | 1-1 |