[2] Club América 2-1 Club León [17] 2021-03-07 01:00
Estádio: Estadio Azteca Round: 10
Juiz: Eduardo Galvan Basulto Home Manager: Santiago Solari Away Manager: Ignacio Ambriz
Head to Head
| México - Liga MX | 2020/10/20 02:00 | Club León v Club América | L | 3-2 |
| México - Liga MX | 2019/07/28 00:00 | Club León v Club América | D | 0-0 |
| México - Liga MX | 2019/05/20 01:06 | Club León v Club América | W | 0-1 |
| México - Liga MX | 2019/05/17 01:30 | Club América v Club León | L | 0-1 |
| México - Liga MX | 2019/02/10 01:00 | Club América v Club León | L | 0-3 |
| México - Liga MX | 2018/08/23 00:00 | Club León v Club América | L | 2-0 |
| México - Liga MX | 2018/03/11 03:00 | Club América v Club León | W | 2-0 |
| México - Liga MX | 2017/09/28 00:06 | Club León v Club América | L | 2-1 |
Home History
| México - Liga MX | 2021/03/04 03:06 | Tijuana v Club América | W | 0-2 |
| México - Liga MX | 2021/02/28 01:00 | Club América v Pachuca | W | 2-0 |
| México - Liga MX | 2021/02/14 03:00 | Club América v Querétaro | W | 2-1 |
| México - Liga MX | 2021/02/07 01:00 | Club América v Puebla | W | 1-0 |
| México - Liga MX | 2021/02/01 01:06 | Santos Laguna v Club América | D | 1-1 |
| México - Liga MX | 2021/01/27 02:30 | Club América v Juárez FC | W | 2-0 |
| México - Liga MX | 2021/01/17 03:06 | Monterrey v Club América | L | 1-0 |
| México - Liga MX | 2021/01/10 03:00 | Club América v Atlético San Luís | W | 2-1 |
Away History
| México - Liga MX | 2021/03/03 03:00 | Club León v Puebla | L | 1-2 |
| México - Liga MX | 2021/02/28 03:00 | Club León v Cruz Azul | L | 0-1 |
| México - Liga MX | 2021/02/21 18:00 | Pumas v Club León | W | 0-1 |
| México - Liga MX | 2021/02/13 03:06 | Tijuana v Club León | L | 2-0 |
| México - Liga MX | 2021/02/09 03:00 | Club León v Chivas Guadalajara | L | 1-3 |
| México - Liga MX | 2021/02/02 03:00 | Club León v Atlético San Luís | W | 3-1 |
| México - Liga MX | 2021/01/19 03:00 | Club León v Pachuca | D | 0-0 |
| México - Liga MX | 2021/01/10 01:00 | Tigres UANL v Club León | L | 2-0 |