[5] Club Nacional 1-1 River Plate Asuncion [6] 2021-10-29 22:30
Estádio: Estádio Arsenio Erico Round: 14
Juiz: Jose Mendez Home Manager: Rodrigo Lopez Away Manager: Celso Ayala
Head to Head
| Paraguai - División Profesional | 2021/08/13 23:45 | River Plate Asuncion v Club Nacional | L | 1-0 |
| Paraguai - División Profesional | 2021/05/24 00:00 | Club Nacional v River Plate Asuncion | L | 0-1 |
| Paraguai - División Profesional | 2021/03/13 21:30 | River Plate Asuncion v Club Nacional | D | 0-0 |
| Paraguai - División Profesional | 2020/12/12 21:30 | River Plate Asuncion v Club Nacional | D | 1-1 |
| Paraguai - División Profesional | 2020/09/21 23:00 | Club Nacional v River Plate Asuncion | L | 1-2 |
| Paraguai - División Profesional | 2020/07/21 20:00 | River Plate Asuncion v Club Nacional | D | 1-1 |
| Paraguai - División Profesional | 2019/10/25 23:00 | Club Nacional v River Plate Asuncion | D | 1-1 |
| Paraguai - División Profesional | 2019/08/03 22:00 | River Plate Asuncion v Club Nacional | W | 0-1 |
Home History
| Paraguai - División Profesional | 2021/10/24 23:15 | Club Libertad v Club Nacional | W | 1-2 |
| Paraguai - División Profesional | 2021/10/16 22:30 | Club Nacional v Sportivo Luqueño | D | 0-0 |
| Paraguai - División Profesional | 2021/10/03 21:00 | Club Guaraní v Club Nacional | D | 1-1 |
| Paraguai - División Profesional | 2021/09/25 22:00 | Club Nacional v 12 de Octubre | D | 1-1 |
| Paraguai - División Profesional | 2021/09/21 00:00 | Club Olimpia v Club Nacional | W | 1-2 |
| Paraguai - División Profesional | 2021/09/10 23:30 | Club Nacional v Club Sol de América | D | 1-1 |
| Paraguai - División Profesional | 2021/08/29 00:15 | Cerro Porteño v Club Nacional | W | 0-2 |
| Taça do Paraguai | 2021/08/25 19:15 | Club 1 de Marzo Pilar v Club Nacional | L | 3-0 |
Away History
| Paraguai - División Profesional | 2021/10/23 21:00 | River Plate Asuncion v Club Sol de América | L | 0-2 |
| Paraguai - División Profesional | 2021/10/18 23:30 | Cerro Porteño v River Plate Asuncion | L | 2-0 |
| Taça do Paraguai | 2021/10/06 20:30 | River Plate Asuncion v CA Tembetary | L | 0-1 |
| Paraguai - División Profesional | 2021/10/03 00:15 | River Plate Asuncion v Guairena FC | D | 1-1 |
| Paraguai - División Profesional | 2021/09/26 22:00 | River Plate Asuncion v Club Olimpia | L | 1-2 |
| Taça do Paraguai | 2021/09/21 21:00 | Deportivo Karai Chive v River Plate Asuncion | W | 2-4 |
| Paraguai - División Profesional | 2021/09/18 00:15 | River Plate Asuncion v Club Libertad | L | 0-1 |
| Paraguai - División Profesional | 2021/09/11 22:00 | Sportivo Luqueño v River Plate Asuncion | W | 0-2 |