[5] Club León 0-3 Tigres UANL [3] 2022-03-12 23:00
Estádio: Estádio Leon Round: 10
Juiz: Fernando Guerrero Home Manager: Ariel Holan Away Manager: Miguel Herrera
Head to Head
| México - Liga MX | 2021/12/05 03:00 | Club León v Tigres UANL | W | 2-1 |
| México - Liga MX | 2021/12/02 03:00 | Tigres UANL v Club León | L | 2-1 |
| México - Liga MX | 2021/09/12 00:00 | Tigres UANL v Club León | D | 2-2 |
| México - Liga MX | 2021/01/10 01:00 | Tigres UANL v Club León | L | 2-0 |
| México - Liga MX | 2020/09/09 22:00 | Club León v Tigres UANL | D | 1-1 |
| México - Liga MX | 2019/09/01 00:00 | Tigres UANL v Club León | D | 1-1 |
| México - Liga MX | 2019/05/27 01:06 | Club León v Tigres UANL | D | 0-0 |
| México - Liga MX | 2019/05/24 01:45 | Tigres UANL v Club León | L | 1-0 |
Home History
| CONCACAF - Taça dos Campeões | 2022/03/09 03:00 | Seattle Sounders v Club León | L | 3-0 |
| México - Liga MX | 2022/03/05 03:00 | Juárez FC v Club León | W | 0-1 |
| México - Liga MX | 2022/03/02 03:00 | Club León v Monterrey | D | 0-0 |
| México - Liga MX | 2022/02/26 01:00 | Necaxa v Club León | W | 0-1 |
| CONCACAF - Taça dos Campeões | 2022/02/23 03:15 | Club León v Guastatoya | W | 1-0 |
| México - Liga MX | 2022/02/20 03:00 | Club León v Chivas Guadalajara | W | 2-1 |
| CONCACAF - Taça dos Campeões | 2022/02/16 23:00 | Guastatoya v Club León | W | 0-2 |
| México - Liga MX | 2022/02/13 18:00 | Pumas v Club León | L | 2-1 |
Away History
| México - Liga MX | 2022/03/03 01:00 | Tigres UANL v Cruz Azul | D | 2-2 |
| México - Liga MX | 2022/02/26 03:00 | Juárez FC v Tigres UANL | W | 2-3 |
| México - Liga MX | 2022/02/20 01:00 | Tigres UANL v Atlético San Luís | W | 2-1 |
| México - Liga MX | 2022/02/12 23:00 | Chivas Guadalajara v Tigres UANL | W | 1-3 |
| México - Liga MX | 2022/02/07 02:00 | Tigres UANL v Mazatlán FC | W | 4-3 |
| México - Liga MX | 2022/01/23 18:00 | Pumas v Tigres UANL | W | 1-2 |
| México - Liga MX | 2022/01/16 01:00 | Tigres UANL v Puebla | L | 0-2 |
| México - Liga MX | 2022/01/13 02:06 | Santos Laguna v Tigres UANL | D | 1-1 |