[15] PHI Flyers 3-4 BUF Sabres [6] 2022-04-16 23:00
Estádio: Centro KeyBank
Home Manager: Don Granato Away Manager: Mike Yeo
Head to Head
| NHL | 2022/01/22 18:00 | PHI Flyers v BUF Sabres | L | 3-6 |
| NHL | 2021/04/11 18:00 | BUF Sabres v PHI Flyers | L | 5-3 |
| NHL | 2021/03/31 23:30 | PHI Flyers v BUF Sabres | L | 1-6 |
| NHL | 2021/03/29 23:00 | PHI Flyers v BUF Sabres | W | 4-3 |
| NHL | 2021/03/10 00:00 | BUF Sabres v PHI Flyers | W | 4-5 |
| NHL | 2021/02/28 20:00 | PHI Flyers v BUF Sabres | W | 3-0 |
| NHL | 2021/02/27 18:00 | PHI Flyers v BUF Sabres | W | 3-0 |
| NHL | 2021/01/20 00:00 | BUF Sabres v PHI Flyers | W | 0-3 |
| NHL | 2021/01/19 00:30 | BUF Sabres v PHI Flyers | L | 6-1 |
| NHL | 2020/03/08 00:00 | BUF Sabres v PHI Flyers | W | 1-3 |
| NHL | 2019/12/20 00:00 | BUF Sabres v PHI Flyers | W | 1-6 |
| NHL | 2019/02/27 00:00 | BUF Sabres v PHI Flyers | W | 2-5 |
| NHL | 2018/12/08 18:00 | PHI Flyers v BUF Sabres | W | 6-2 |
| NHL | 2018/11/22 00:30 | PHI Flyers v BUF Sabres | L | 2-5 |
| NHL | 2018/01/07 18:00 | BUF Sabres v PHI Flyers | W | 1-4 |
| NHL | 2017/12/23 00:00 | PHI Flyers v BUF Sabres | L | 2-4 |
| NHL | 2017/12/15 00:00 | BUF Sabres v PHI Flyers | W | 1-2 |
| NHL | 2017/03/08 00:30 | PHI Flyers v BUF Sabres | W | 6-3 |
| NHL | 2017/01/11 00:00 | PHI Flyers v BUF Sabres | L | 1-4 |
| NHL | 2016/10/25 23:30 | BUF Sabres v PHI Flyers | W | 3-4 |