| NCAAF | 11/18 17:00 | 1 | Eastern Illinois v Robert Morris | W | 28-14 | |
| NCAAF | 11/11 18:00 | 1 | Tennessee State v Eastern Illinois | W | 17-30 | |
| NCAAF | 11/04 19:00 | 1 | Eastern Illinois v Lindenwood | W | 16-10 | |
| NCAAF | 10/21 19:00 | 1 | Bryant v Eastern Illinois | W | 24-25 | |
| NCAAF | 10/14 19:00 | 1 | Eastern Illinois v SE Missouri State | L | 28-35 | |
| NCAAF | 10/07 19:00 | 1 | Tennessee Martin v Eastern Illinois | L | 28-27 | |
| NCAAF | 09/30 23:00 | 1 | Eastern Illinois v Northwestern State | W | 19-10 | |
| NCAAF | 09/23 19:00 | 1 | McNeese State v Eastern Illinois | W | 28-31 | |
| NCAAF | 09/16 19:00 | 1 | Illinois State v Eastern Illinois | W | 13-14 | |
| NCAAF | 09/09 18:00 | 1 |
[17] Eastern Illinois
v
Bowling Green
[101] 
|
L | 15-38 | |
| NCAAF | 08/31 22:00 | 1 | [4] Eastern Illinois v Indiana State [4] | W | 27-0 | |
| NCAAF | 11/19 20:00 | 1 | Eastern Illinois v Tennessee Martin | L | 31-34 | |
| NCAAF | 11/12 20:00 | 1 | SE Missouri State v Eastern Illinois | L | 31-7 | |
| NCAAF | 11/06 00:00 | 1 | Eastern Illinois v McNeese State | L | 15-29 | |
| NCAAF | 10/29 19:00 | 1 | Tennessee Tech v Eastern Illinois | L | 20-17 | |
| NCAAF | 10/22 19:00 | 1 | Eastern Illinois v Tennessee State | L | 17-37 | |
| NCAAF | 10/15 19:00 | 1 | Lindenwood v Eastern Illinois | L | 37-34 | |
| NCAAF | 10/08 19:00 | 1 | Northwestern State v Eastern Illinois | W | 27-35 | |
| NCAAF | 09/24 21:00 | 1 | Eastern Illinois v Murray State | W | 35-21 | |
| NCAAF | 09/17 23:30 | 1 | [92] Eastern Illinois v Illinois State [58] | L | 7-35 | |
| NCAAF | 09/10 23:00 | 1 | Chattanooga v Eastern Illinois | L | 38-20 | |
| NCAAF | 09/02 00:00 | 1 |
[3] Eastern Illinois
v
Northern Illinois
[57] 
|
L | 27-34 | |
| NCAAF | 11/20 18:00 | 1 | Murray State v Eastern Illinois | L | 20-13 | |
| NCAAF | 11/06 19:00 | 1 |
Eastern Illinois
v
Austin Peay
|
L | 26-42 | |
| NCAAF | 10/30 18:00 | 1 | Eastern Illinois v SE Missouri State | L | 15-38 | |
| NCAAF | 10/23 19:00 | 1 | Tennessee State v Eastern Illinois | L | 28-0 | |
| NCAAF | 10/16 19:00 | 1 | Tennessee Martin v Eastern Illinois | L | 28-17 | |
| NCAAF | 10/02 21:00 | 1 | Eastern Illinois v Murray State | L | 6-22 | |
| NCAAF | 09/25 18:30 | 1 | Eastern Illinois v Tennessee Tech | W | 28-14 | |
| NCAAF | 09/18 23:00 | 1 | Illinois State v Eastern Illinois | L | 31-24 |