| ITF - W25 Getxo | 07/13 10:30 | 28 | [453] Despina Papamichail v Irene B Escorihuela [392] | 6-4,6-7,6-3 | |
| ITF - W25 Getxo | 07/12 11:00 | 27 | [258] Nadia Podoroska v Despina Papamichail [453] | 0-6,4-6 | |
| ITF - W25 Getxo | 07/11 09:00 | 26 | [453] Despina Papamichail v Lina Gjorcheska [372] | 7-5,6-3 | |
| ITF - W25 Getxo | 07/09 18:25 | 25 | Mercedes Aristegui v Despina Papamichail | 2-6,0-6 | |
| ITF - W25 Den Haag | 07/04 09:15 | 26 | [453] Despina Papamichail v Valentina Ivakhnenko [251] | 5-7,4-6 | |
| ITF - W25 Den Haag | 07/03 12:15 | 25 | Monika Kilnarova v Despina Papamichail | 0-6,6-1,2-6 | |
| ITF - W25 Den Haag | 07/02 09:45 | 54 | Despina Papamichail v Sem Wensveen | 7-5,6-0 | |
| ITF - W25 Den Haag | 07/01 09:30 | 54 | Despina Papamichail v Anna Klasen | 6-0,6-1 | |
| ITF - W25 Ystad | 06/20 11:25 | 26 | [409] Jule Niemeier v Despina Papamichail [456] | 6-4,6-3 | |
| ITF - W25 Ystad | 06/19 10:05 | 25 | Viktoria Morvayova v Despina Papamichail | 4-6,1-6 | |
| ITF - W60 Barcelona | 06/12 10:40 | 25 | [463] Despina Papamichail v Marina B Ribera [432] | 4-6,6-4,4-6 | |
| ITF - W60 Barcelona | 06/10 14:10 | 54 | [479] Agnes Bukta v Despina Papamichail [463] | 0-6,6-0,5-10 | |
| ITF - W60 Barcelona | 06/10 08:25 | 54 | Louise Lampla v Despina Papamichail | 0-6,0-6 | |
| ITF - W15 Banja Luka | 06/06 07:00 | 25 | Despina Papamichail v Nika Radisic | 6-4,6-7,2-6 | |
| ITF - W25 SM de Montbui | 05/30 10:10 | 26 | [474] Despina Papamichail v Nadia Podoroska [272] | 2-6,4-6 | |
| ITF - W25 SM de Montbui | 05/29 13:15 | 25 | [415] Irene B Escorihuela v Despina Papamichail [474] | Retired | |
| ITF - W25 SM de Montbui | 05/28 11:10 | 54 | Despina Papamichail v Nadja B Christians | 6-0,6-3 | |
| ITF - W25 Jerusalém | 05/21 12:35 | 25 | [472] Despina Papamichail v Yuliya Hatouka [334] | 3-6,2-6 | |
| ITF - W60 La Bisbal | 05/13 07:30 | 45 | [483] Despina Papamichail v Andrea Gamiz [358] | 4-6,3-6 | |
| ITF - W25 Monzón | 05/09 10:00 | 26 | [303] Valeriya Strakhova v Despina Papamichail [482] | 1-6,6-3,7-6 | |
| ITF - W25 Monzón | 05/08 09:00 | 25 | [272] Jodie Anna Burrage v Despina Papamichail [482] | 2-6,4-6 | |
| ITF - W25 Monzón | 05/07 09:45 | 45 | Despina Papamichail v Olga Parres Azcoitia | 6-2,6-3 | |
| ITF - W25 Monzón | 05/06 13:35 | 45 | Despina Papamichail v Esther L Alcaraz | 6-2,6-3 | |
| ITF W60 Les Franqueses | 04/29 14:35 | 54 | Despina Papamichail v Ioana Loredana Rosca | 6-3,3-6,7-10 | |
| ITF W60 Les Franqueses | 04/29 11:00 | 54 | Despina Papamichail v Julia Payola | 6-1,6-1 | |
| ITF - W15 Cairo | 04/27 09:00 | 28 | Despina Papamichail v Simona Waltert | 6-3,3-6,3-6 | |
| ITF - W15 Cairo | 04/26 08:00 | 27 | Despina Papamichail v Charlotte Roemer | 6-0,6-0 | |
| ITF - W15 Cairo | 04/25 08:00 | 26 | Despina Papamichail v Sem Wensveen | 6-3,7-5 | |
| ITF - W15 Cairo | 04/24 08:05 | 25 | Despina Papamichail v Kajsa Rinaldo Persson | 6-1,6-7,6-4 | |
| ITF - W15 Cairo | 04/21 08:00 | 29 | Nastja Kolar v Despina Papamichail | 3-6,6-4,4-6 |
Despina Papamichail (Greek: Δέσποινα Παπαμιχαήλ; born 9 February 1993) is a Greek professional tennis player. She has a career-high singles ranking of world No. 147, reached on 20 June 2022. Her highest doubles ranking is No. 93, achieved on 4 December 2023. Papamichail has won two doubles titles on the WTA Challenger Tour as well as 15 singles and 37 doubles titles on the ITF Women's Circuit.
Playing for the Greece Fed Cup team, Papamichail has a win–loss record of 31–29 (as of May 2024).
In June 2021, Papamichail won the inaugural $60k Charleston Pro event by defeating Gabriela Cé, her first title above $25k level.
She made her WTA Tour main-draw debut 2021 at the WTA 500 event in Abu Dhabi.
At the 2023 United Cup, she started the season with a win over Isabella Shinikova.
Later, she qualified for the Pan Pacific Open and defeated lucky loser Sakura Hosogi.